Is it possible to make a 2D Game with this engine that would be cross platform?

What sort of technique could be used to load a Flat 2D world?

eg, pacman

It's possible. You would have to write a lot of custom code, like your own animated sprite class and such, though. Esenthel has the function for displaying images on screen coordinates, but there's not much else that I've seen that is specifically geared towards 2D games.
Have you considered a 3D game locked into 2 dimensions, so it looks good but is still basically 2D? (I believe Trine is a good example.)

ImageAtlas added in last SDK (currently only released on Android) is perfect for drawing animated images.